Magnus Ingelman-Sundberg, Ph.D.
is Professor of Physiology and Pharmacology, and Head of the
Section of Pharmacogenetics at the Karolinska Institute in Sweden.
He is the Chairman of the Editorial Board for Pharmacogenetics and
Genomics. In 2008 he was named to the Nobel Assembly. Dr.
Ingelman-Sundberg has authored over 350 original publications. Dr.
Ingelman-Sundberg's research has focused on the function,
regulation, and pharmacogenetics of CYP. He has emerged as a
leading scientist in characterizing novel CYP polymorphisms and
elucidating their clinical significance. Among his pioneering
findings is the importance of CYP2D6 gene duplications in causing
an ultrarapid metabolizer phenotype that renders patients
non-responsive to antidepressants and prone to adverse effects of
codeine. His laboratory is currently pursuing genetic as well as
epigenetic reasons for interindividual variability CYP3A4 and
CYP1A2 expression. Recently his group identified new extrahepatic
CYPs that are overexpressed in certain cancer cells and may prove
to be novel drug targets. He will be involved in the development of
the education curriculum focusing on pharmacogenomics primer
concepts and clinical applications in concentrated therapeutic
Karen S. Hudmon, Dr.P.H., M.S., R.Ph.
is Associate Professor, School of Pharmacy and Pharmaceutical
Sciences, Purdue University. Dr. Hudmon's research involves (1) the
study of predictors of smoking among adolescents and young adults;
(2) the treatment of tobacco use and dependence through expansion
of the clinician's role in cessation; (3) understanding genetics as
they relate to tobacco use and dependence; and (4) medication
compliance for chronic disease. She has co-coordinated an effort to
develop, evaluate, and disseminate a comprehensive tobacco
cessation training program, Rx for Change: Clinician-Assisted
Tobacco Cessation, for students in the health professions. This
program is being disseminated to health professional schools across
the US and has witnessed broadscale adoption. She will assist in
evaluation of the education program to the different audience
groups and delivery methods.